Reflecting on this past week’s lecture, I found that Professor Johnson’s question concerning the musical affect of the sonification, given that prions are associated with terrible neurological diseases such as Creutzfeldt-Jakob disease. Using music, we can codify the emotional data and its significance in human life, drawing together music and science. The Texas Wesleyan group’s prion music did a superb job capturing the structural aspects of the prion, utilizing string instruments to set a sort of alluring and daunting mood. Looking at the structure of the Prion protein, the precursor indicates that there is a signal sequence, octapeptide repeat region, conserved hydrophobic region, alpha helix, beta strand, and cysteines of disulfide linkage. I particularly enjoyed how the group produced a harmonic line whose dissonance represented the destructive interaction between the misfolded and normal proteins. I wanted to replicate this sort of destructive interaction and lack of cohesion between the abnormal and normal proteins by sorting through the amino acid sequence of the prion and then transcribing the amino acids into simple notes. Although I would’ve preferred to use complex chords to provide a more rich and filling sound, that seems to difficult given my limited experience in music. Furthermore, it would be even more brilliant if I could assign a protein to a different instrument.