When certain proteins are exposed to heat or chemicals, they become denatured, i.e. change state or qualities. Their secondary and tertiary structures are disrupted, while it’s primary structure still remains intact. For instance, when you boil an egg, the protein … Continue reading
In class we have spent a lot of time discussing all of the negative implications that prions can have on the body. However in researching prion folding, I came across a study conducted by Susan Lindquist that found that blocking … Continue reading
My piece shows part of the Prion Protein’s structure. I am attaching a photo of the Prion Protein as I found it: . I tried to show the structure by dipping the ink in the water and creating the atoms and … Continue reading
This is the PrPC to PrPSc. The painting depicts normal prions becoming infected by abnormal prions. For example, on the bottom right one can see an abormal prion using its tentacles to infect the normal prions in the middle, … Continue reading
This week’s lecture solidified what happens when the normal prion (PrP^C) transforms into the abnormal prion (PrP^Sc). In the tertiary structure of the normal prion, there is an high proportion of alpha helices relative to the proportions of beta sheets … Continue reading
I chose to depict the transformation of healthy prion proteins into the rapid, violent and permanent digression to a wasting disease. I utilized a wet background to initiate the original paint application.Other skills were straw blowing and allowing paint … Continue reading
I chose to represent these two amino acids, respectively Alanine and Tyrosine. I thought the pastel colors represented with the help of different liquids and this specific kind of paper were very interesting, but not representative of the diminished … Continue reading
Through an artistic piece, I was able to show alpha-helices changing into beta sheets. My piece represents the chaos that wrongly-folded prions can create within a host. The main focus is the faint oval with circles representing PrPC and PrPSc. … Continue reading
I thoroughly enjoyed the art lectures given in the past week, particularly in regards to the use of specific chemical liquids to create colors on a biodegradable sheet of paper essentially made from food. The colors reflected beautiful, soft pastels … Continue reading
I decided to use the ink drawing methods shown to our class by Daniela Rivera. To apply the ink I used variations on the ink dripping and blowing technique as well as using a twig and sponge. I explored how … Continue reading